For now, the data on the likely and plausible effects of COVID-19 vaccines on SARS-CoV-2 Spike and RBD protein Ab production from infection are absolutely damning, and this is critical information that should be incorporated into public health policy now.

In short, the data suggest – and the precautionary principle supports the position that those with prior COVID-19 infections should not be vaccinated until we more fully understand the effects of COVID-19 vaccines on broad, durable, and in some cases hard-won, natural immunity.

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